Pemeriksaan Kadar SGOT dan SGPT sebagai Upaya Deteksi Dini Gangguan Fungsi Hati pada Komunitas Dewasa Sekolah Mutiara Bangsa
DOI:
https://doi.org/10.58812/jpws.v5i07.3554Kata Kunci:
Fungsi Hati, Pengabdian Kepada Masyarakat, Skrining Kesehatan, SGOT, SGPTAbstrak
Kegiatan pengabdian kepada masyarakat ini bertujuan menggambarkan kadar serum glutamic oxaloacetic transaminase (SGOT) dan serum glutamic pyruvic transaminase (SGPT) sebagai upaya deteksi dini gangguan fungsi hati pada masyarakat dewasa produktif. Sebanyak 45 peserta mengikuti pemeriksaan SGOT dan SGPT menggunakan metode skrining sederhana. Rerata usia peserta sebesar 34,69 dengan standar deviasi 9,05 tahun dan mayoritas berjenis kelamin perempuan (80,0%). Pemeriksaan SGOT menunjukkan rerata sebesar 24,47 dengan standar deviasi 5,20 U/L dan median 24,00 U/L (14,00–35,00 U/L), sedangkan SGPT menunjukkan rerata sebesar 22,20 dengan standar deviasi 4,98 U/L dan median 22,00 U/L (15,00–38,00 U/L). Rerata kadar SGOT dan SGPT pada laki-laki cenderung lebih tinggi dibandingkan perempuan, meskipun seluruh nilai masih berada dalam rentang normal. Hasil ini menunjukkan bahwa fungsi hati peserta secara umum masih baik. Oleh karena itu, skrining fungsi hati, edukasi pola hidup sehat, aktivitas fisik rutin, dan pengendalian berat badan penting dilakukan untuk mencegah gangguan metabolik dan penyakit hati pada masyarakat dewasa produktif.
Referensi
Balakrishnan, M., & Rehm, J. (2024). A public health perspective on mitigating the global burden of chronic liver disease. Hepatology, 79(2), 451–459. https://doi.org/10.1097/HEP.0000000000000679
Cherubini, A., Della Torre, S., Pelusi, S., & Valenti, L. (2024). Sexual dimorphism of metabolic dysfunction-associated steatotic liver disease. Trends in Molecular Medicine, 30(12), 1126–1136. https://doi.org/10.1016/j.molmed.2024.05.013
Eng, P. C., Forlano, R., Tan, T., Manousou, P., Dhillo, W. S., & Izzi-Engbeaya, C. (2023). Non-alcoholic fatty liver disease in women – Current knowledge and emerging concepts. JHEP Reports, 5(10), 100835. https://doi.org/10.1016/j.jhepr.2023.100835
Grob, S. R., Suter, F., Katzke, V., & Rohrmann, S. (2023). The Association between Liver Enzymes and Mortality Stratified by Non-Alcoholic Fatty Liver Disease: An Analysis of NHANES III. Nutrients, 15(13), 3063. https://doi.org/10.3390/nu15133063
Hawkins, G. T., Chung, C. S., Hertz, M. F., & Antolin, N. (2023). The School Environment and Physical and Social‐Emotional Well‐Being: Implications for Students and School Employees. Journal of School Health, 93(9), 799–812. https://doi.org/10.1111/josh.13375
Heeren, J., & Scheja, L. (2021). Metabolic-associated fatty liver disease and lipoprotein metabolism. Molecular Metabolism, 50, 101238. https://doi.org/10.1016/j.molmet.2021.101238
Huang, C.-X., Zhou, X.-D., Pan, C. Q., & Zheng, M.-H. (2024). Screening for metabolic dysfunction-associated fatty liver disease: Time to discard the emperor’s clothes of normal liver enzymes? World Journal of Gastroenterology, 30(22), 2839–2842. https://doi.org/10.3748/wjg.v30.i22.2839
Kjaergaard, M., Lindvig, K. P., Thorhauge, K. H., Johansen, S., Hansen, J. K., Andersen, P., Hansen, C. D., Schnefeld, H. L., Bech, K. T., Torp, N., Israelsen, M., Detlefsen, S., Graupera, I., Gines, P., Krag, A., & Thiele, M. (2024). Screening for Fibrosis Promotes Lifestyle Changes: A Prospective Cohort Study in 4796 Individuals. Clinical Gastroenterology and Hepatology, 22(5), 1037-1047.e9. https://doi.org/10.1016/j.cgh.2023.12.018
Kočar, E., Blagotinšek Cokan, K., Kreft, T., Režen, T., & Rozman, D. (2025). The importance of sex dimorphism in liver metabolism and progressive liver diseases. Biology of Sex Differences, 17(1), 14. https://doi.org/10.1186/s13293-025-00811-7
Mohammadi, T., & Mohammadi, B. (2024). Screening the General Population for Non-Alcoholic Fatty Liver Disease: Model Development and Validation. Archives of Medical Research, 55(3), 102987. https://doi.org/10.1016/j.arcmed.2024.102987
Polpichai, N., Saowapa, S., Danpanichkul, P., Chan, S.-Y., Sierra, L., Blagoie, J., Rattananukrom, C., Sripongpun, P., & Kaewdech, A. (2024). Beyond the Liver: A Comprehensive Review of Strategies to Prevent Hepatocellular Carcinoma. Journal of Clinical Medicine, 13(22), 6770. https://doi.org/10.3390/jcm13226770
Raya-Cano, E., Molina-Luque, R., Vaquero-Abellán, M., Molina-Recio, G., Jiménez-Mérida, R., & Romero-Saldaña, M. (2023). Metabolic syndrome and transaminases: systematic review and meta-analysis. Diabetology & Metabolic Syndrome, 15(1), 220. https://doi.org/10.1186/s13098-023-01200-z
Singh, P., Bsrat, M., Huang, S., Zaher, A., Lin, Z., & Weisberg, I. (2023). S3908 A Quality Improvement Project to Screen, Risk Stratify, and Manage Patients With Nonalcoholic Fatty Liver Disease. American Journal of Gastroenterology, 118(10S), S2493–S2494. https://doi.org/10.14309/01.ajg.0000965272.86284.2b
Takahata, Y., Takahashi, A., Anzai, Y., Abe, N., Sugaya, T., Fujita, M., Hayashi, M., Abe, K., & Ohira, H. (2024). Lifestyle factors affecting new-onset nonalcoholic fatty liver disease. Preventive Medicine Reports, 37, 102577. https://doi.org/10.1016/j.pmedr.2023.102577
Wang, D. Q. ‐H., Portincasa, P., & Neuschwander‐Tetri, B. A. (2013). Steatosis in the Liver. In Comprehensive Physiology (pp. 1493–1532). Wiley. https://doi.org/10.1002/cphy.c130001
Wu, X.-N., Xue, F., Zhang, N., Zhang, W., Hou, J.-J., Lv, Y., Xiang, J.-X., & Zhang, X.-F. (2024). Global burden of liver cirrhosis and other chronic liver diseases caused by specific etiologies from 1990 to 2019. BMC Public Health, 24(1), 363. https://doi.org/10.1186/s12889-024-17948-6
Yao, N., Kowalczyk, M., Gregory, L., Cheatham, J., DeClemente, T., Fox, K., Ignoffo, S., & Volerman, A. (2023). Community health workers’ perspectives on integrating into school settings to support student health. Frontiers in Public Health, 11. https://doi.org/10.3389/fpubh.2023.1187855
Zhang, J.-W., Zhang, N., Lyu, Y., & Zhang, X.-F. (2025). Influence of Sex in the Development of Liver Diseases. Seminars in Liver Disease, 45(01), 015–032. https://doi.org/10.1055/a-2516-0261
Unduhan
Diterbitkan
Terbitan
Bagian
Lisensi
Hak Cipta (c) 2026 Lydia Tantoso, Alexander Halim Santoso

Artikel ini berlisensiCreative Commons Attribution-ShareAlike 4.0 International License.


















