Skrining Fungsi Hati melalui Pemeriksaan SGOT dan SGPT pada Karyawan Perkantoran di Sudirman
DOI:
https://doi.org/10.58812/jpws.v4i12.2926Kata Kunci:
Edukasi Kesehatan, Fungsi Hati, Karyawan Perkantoran, SGOT, SGPTAbstrak
Gangguan fungsi hati dapat tidak terdeteksi sejak dini, padahal deteksi awal penting untuk mencegah komplikasi jangka panjang. Kegiatan PKM ini bertujuan melakukan skrining fungsi hati pada karyawan perkantoran di daerah Sudirman melalui pemeriksaan SGOT dan SGPT sebagai upaya preventif. Pendekatan Plan-Do-Check-Act (PDCA) welly@fk.untar.ac.id dilakukan pada 57 karyawan. Tahapan kegiatan meliputi edukasi kesehatan mengenai fungsi hati, faktor risiko, pola makan seimbang, hidrasi, dan aktivitas fisik, diikuti pengambilan sampel darah untuk pemeriksaan SGOT dan SGPT menggunakan metode laboratorium standar. Hasil dicatat, dikonsultasikan secara individual, dan diklasifikasikan ke dalam kategori normal atau meningkat untuk meningkatkan kesadaran peserta mengenai kesehatan hati. Mayoritas peserta memiliki kadar SGOT dan SGPT dalam batas normal, menunjukkan fungsi hati yang relatif baik. Variasi individu yang masih terdapat pada nilai enzim hati menekankan pentingnya deteksi dini dan pemantauan berkala. Partisipasi aktif peserta juga menunjukkan tingginya kesadaran terhadap edukasi kesehatan yang diberikan. Pemeriksaan SGOT dan SGPT di tempat kerja efektif sebagai deteksi dini gangguan fungsi hati sekaligus sarana edukasi kesehatan. Disarankan pelaksanaan skrining rutin, program edukasi berkelanjutan, dan penelitian lanjutan dengan cakupan lebih luas untuk memahami risiko gangguan fungsi hati pada pekerja perkantoran di daerah Sudirman.
Referensi
Alcohol-related deaths: liver cirrhosis, death rates (15+), per 100,000 population, age-standardized. (n.d.). Retrieved August 31, 2025, from https://www.who.int/data/gho/data/indicators/indicator-details/GHO/liver-cirrhosis-age-standardized-death-rates-(15-)-per-100-000-population-unpublish
Bhargava, B., Rao, P. N., Kulkarni, A. V., Vishnubhotla, R., Pramod, N., Anitha, C. T., & Mahadev, K. (2025). Prevalence of metabolic dysfunction-associated fatty liver disease among information technology employees in India. Scientific Reports, 15(1), 1–14. https://doi.org/10.1038/S41598-025-91482-2;SUBJMETA=308,4020,692,699;KWRD=DISEASES,GASTROENTEROLOGY,MEDICAL+RESEARCH
Burra, P., Cammà, C., Invernizzi, P., Marra, F., & Pompili, M. (2025). Does the hepatologist still need to rely on aminotransferases in clinical practice? A reappraisal of the role of a classic biomarker in the diagnosis and clinical management of chronic liver diseases. Annals of Hepatology, 30(1), 101900. https://doi.org/10.1016/J.AOHEP.2025.101900
Chinnappan, R., Mir, T. A., Alsalameh, S., Makhzoum, T., Adeeb, S., Al-Kattan, K., & Yaqinuddin, A. (2023). Aptasensors Are Conjectured as Promising ALT and AST Diagnostic Tools for the Early Diagnosis of Acute Liver Injury. Life 2023, Vol. 13, Page 1273, 13(6), 1273. https://doi.org/10.3390/LIFE13061273
Devarbhavi, H., Asrani, S. K., Arab, J. P., Nartey, Y. A., Pose, E., & Kamath, P. S. (2023). Global burden of liver disease: 2023 update. Journal of Hepatology, 79(2), 516–537. https://doi.org/10.1016/J.JHEP.2023.03.017
Drake, I., Giontella, A., Miari, M., Önnerhag, K., Orho-Melander, M., Abecasis, G., Ferrando, A., Baras, A., Cantor, M., Coppola, G., Deubler, A., Economides, A., Lotta, L. A., Overton, J. D., Reid, J. G., Shuldiner, A., Siminovitch, K., Beechert, C., Brian, E. D., … Siceron, S. (2024). Lifestyle and genetic risk of chronic liver disease in metabolically healthy and unhealthy individuals from the general population. JHEP Reports, 6(8), 101105. https://doi.org/10.1016/J.JHEPR.2024.101105
Early Detection, Prevention, and Infections Branch (EPR) – IARC. (n.d.). Retrieved August 31, 2025, from https://www.iarc.who.int/branches-epr/
Gan, C., Yuan, Y., Shen, H., Gao, J., Kong, X., Che, Z., Guo, Y., Wang, H., Dong, E., & Xiao, J. (2025). Liver diseases: epidemiology, causes, trends and predictions. Signal Transduction and Targeted Therapy 2025 10:1, 10(1), 1–36. https://doi.org/10.1038/s41392-024-02072-z
Gupta, S., & Walker, S. (2021). Testing for cirrhosis. Australian Prescriber, 44(6), 197–199. https://doi.org/10.18773/AUSTPRESCR.2021.053
Joo, J. H., Kim, H. J., Park, E. C., & Jang, S. I. (2020). Association between sitting time and non-alcoholic fatty live disease in South Korean population: a cross-sectional study. Lipids in Health and Disease, 19(1), 212. https://doi.org/10.1186/S12944-020-01385-6
Joung, J. Y., Cho, J. H., Kim, Y. H., Choi, S. H., & Son, C. G. (2019). A literature review for the mechanisms of stress‐induced liver injury. Brain and Behavior, 9(3), e01235. https://doi.org/10.1002/BRB3.1235
Khatatbeh, M., Momani, W., Altaani, Z., Saad, R. Al, & Al Bourah, A. R. (2021). Fast Food Consumption, Liver Functions, and Change in Body Weight Among University Students: A Cross-Sectional Study. International Journal of Preventive Medicine, 12(1), 109. https://doi.org/10.4103/IJPVM.IJPVM_194_19
Kisling, L. A., & Das, J. M. (2023). Prevention Strategies. https://www.ncbi.nlm.nih.gov/books/NBK537222/
Lee, A. S., Persoff, J., & Lange, S. M. (2023). Liver Function Tests. Mayo Clinic Medical Manual, 373–387. https://doi.org/10.1201/b14283-48
Mega, A., Marzi, L., Kob, M., Piccin, A., & Floreani, A. (2021). Food and Nutrition in the Pathogenesis of Liver Damage. Nutrients, 13(4), 1326. https://doi.org/10.3390/NU13041326
Peng, X., Li, J., Zhao, H., Lai, J., Lin, J., & Tang, S. (2022). Lifestyle as well as metabolic syndrome and non-alcoholic fatty liver disease: an umbrella review of evidence from observational studies and randomized controlled trials. BMC Endocrine Disorders, 22(1), 1–16. https://doi.org/10.1186/S12902-022-01015-5/TABLES/2
Publikasi | Medkom Menjaga Hati Untuk Kehidupan. (n.d.). Retrieved August 31, 2025, from https://setjen.kemkes.go.id/medkom/detail/menjaga-hati-untuk-kehidupan
Schneider, C. V., Zandvakili, I., Thaiss, C. A., & Schneider, K. M. (2021). Physical activity is associated with reduced risk of liver disease in the prospective UK Biobank cohort. JHEP Reports, 3(3), 100263. https://doi.org/10.1016/J.JHEPR.2021.100263
Sharma, A., & Nagalli, S. (2023). Chronic Liver Disease. Sitaraman and Friedman’s Essentials of Gastroenterology, Second Edition, 227–244. https://doi.org/10.1002/9781119235170.ch15
WHO sounds alarm on viral hepatitis infections claiming 3500 lives each day. (n.d.). Retrieved August 31, 2025, from https://www.who.int/news/item/09-04-2024-who-sounds-alarm-on-viral-hepatitis-infections-claiming-3500-lives-each-day
Wu, W., Ma, W., Yuan, S., Feng, A., Li, L., Zheng, H., Li, S., He, N., Huang, Y., & Lyu, J. (2023). Associations of Unhealthy Lifestyle and Nonalcoholic Fatty Liver Disease With Cardiovascular Healthy Outcomes. Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 12(23), e031440. https://doi.org/10.1161/JAHA.123.031440
Zhang, S., Huo, Z., Borné, Y., Meng, G., Zhang, Q., Liu, L., Wu, H., Gu, Y., Sun, S., Wang, X., Zhou, M., Jia, Q., Song, K., Ma, L., Qi, L., & Niu, K. (2024). Adherence to a healthy lifestyle including sleep and sedentary behaviors and risk of metabolic dysfunction-associated steatotic liver disease in Chinese adults. Preventive Medicine, 184, 107971. https://doi.org/10.1016/J.YPMED.2024.107971
Zhang, X., Chen, K., Yin, S., Qian, M., & Liu, C. (2023). Association of leisure sedentary behavior and physical activity with the risk of nonalcoholic fatty liver disease: a two-sample Mendelian randomization study. Frontiers in Nutrition, 10, 1158810. https://doi.org/10.3389/FNUT.2023.1158810/BIBTEX
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Hak Cipta (c) 2025 Welly Hartono Ruslim, Alexander Halim Santoso, Gracienne Gracienne, Eric Hartono, Dianova Soeltanong

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